Search results for ‘Subject term:"prader-willi syndrome"’ Sort:
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Prader-Willi syndrome and hyperphagia: an update
- Author:
- STANLEY K.
- Journal article citation:
- Advances in Mental Health and Intellectual Disabilities, 8(5), 2014, pp.321-330.
- Publisher:
- Emerald
Purpose: Prader-Willi syndrome (PWS) is a genetic disorder characterised by excessive appetite and progressive obesity. The causes of hyperphagia (the desire to keep eating) are unknown and this has implications on treatment limiting the options available. This paper systematically synthesises the latest evidence regarding all causes as well as management of hyperphagia in people with PWS. Design/methodology/approach: A computer-based literature search, citation tracking and related articles search was undertaken. Primary research studies using genetically confirmed Prader-Willi participants specifically focused on the causes and treatment of overeating was included. Studies were described, critically analysed, presented and discussed in the review. Findings: In total, 18 relevant studies were identified. Nine studies were included in the causes of hyperphagia and focused largely on the roles of secretory hormones, and reward-related areas of the brain. Nine studies were included in the management of hyperphagia and related to physical exercise and food control, antidiabetic agents and weight loss surgery. Originality/value: The causes and the management of hyperphagia are still to be determined despite promising findings. The small number and heterogeneity of the included studies and participants limits conclusions. There is the need for future research to use larger systematic studies to validate findings so far. (Edited publisher abstract)
What do parents want?: an analysis of education-related comments made by parents of children with different genetic syndromes
- Authors:
- FIDLER Deborah J., LAWSON John E.
- Journal article citation:
- Journal of Intellectual and Developmental Disability, 28(2), June 2003, pp.196-204.
- Publisher:
- Taylor and Francis
This study explored whether parents of children with three different genetic syndromes, Down syndrome (n~39), Prader-Willi syndrome (n~25), and Williams syndrome (n~26), express divergent desires for modifications in their child's current educational programming. A content analysis was performed on the parents' answers to an open-ended question about how to improve their child's current placement. The parents of children with Down syndrome spontaneously expressed a greater desire for changes or improvements in speech therapy and reading services, the parents of children with Prader-Willi syndrome expressed a desire for increases in adaptive physical education services, and the parents of children with Williams syndrome expressed a desire for increases and modifications to music services and aides in the classroom. Within-syndrome variation was also found in the specific sentiments and desires expressed. Implications for a syndrome-specific approach to special education programming are discussed.