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Dementia patients caregivers quality of life: the pixel study
- Author:
- THOMAS Philippe
- Journal article citation:
- International Journal of Geriatric Psychiatry, 21(1), January 2006, pp.50-56.
- Publisher:
- Wiley
This French survey aimed to determine parameters influencing caregivers' quality of life, and its possible link with patients' quality of life. A scale measuring caregivers' quality of life, developed from data from previous PIXEL studies was used. It is a questionnaire composed of 20 items. The scale was related to the socio-demographic data of both patients and their main caregivers, to the ADRQL scale (Alzheimer Disease Related Quality Life) of Rabins for the QoL of dementia patients, to the patients medical and therapeutic data, specially a neuropsychological inventory: Folstein's cognition test, Cornell's depression scale, the fast battery of frontal assessment, Katz's dependence index, Cummings' neuropsychiatric inventory for behavioural and psychological symptoms of dementia and to a physician evaluation of caregiver's depression. One hundred patients diagnosed with dementia who live at home with their principal caregivers were recruited for this survey. The caregivers' quality of life was correlated to the quality of life of the patients they cared for, the importance of behavioural disorders, and the duration of dementia evolution. Women caregivers had a worse quality of life and were more depressive than men.
Delusions of Japanese patients with Alzheimer's disease
- Authors:
- IKEDA Manabu, et al
- Journal article citation:
- International Journal of Geriatric Psychiatry, 18(6), June 2003, pp.527-532.
- Publisher:
- Wiley
Delusions constitute one of the most prominent psychiatric complications in Alzheimer's disease (AD). However, there is little consensus of the prevalence and associated factors for delusions in AD. 112 consecutive patients with AD were recruited over a one year period and administered the Neuropsychiatric Inventory (NPI). Delusions were present in 53 patients (47.3%). Delusions of theft were the most common type of delusion (75.5% of patients with delusions), followed by misidentification delusions and delusions of suspicion. More hallucination, agitation, and female gender were found in the delusions group. The authors found a high frequency of delusions, particularly of delusions of theft and suggested that gender was associated with the expression of delusions in Japanese patients with AD.
Wandering behaviour in community residing persons with dementia
- Authors:
- KLEIN Diane, et al
- Journal article citation:
- International Journal of Geriatric Psychiatry, 14(4), April 1999, pp.272-279.
- Publisher:
- Wiley
Reports on a study which aims to examine wandering behaviour in elderly demented persons in the community and to generate a statistical model to assess the relative importance factors in predicting wandering behaviour. Results found that wandering behaviour was significantly more prevalent in patients with Alzheimer Dementia, patients with dementia of longer duration, and patients with more severe dementia. Concludes that wandering behaviour among community-residing elderly dementia patients is associated with a number of factors, some of which may be subject to modification. It is possible that management of coexistent psychopathology, particularly of sleep disorder, and of the underlying disease process of AD would help to ameliorate this problematic behavioural disorder.
No association between subjective memory complaints and apolipoprotein E genotype in cognitively intact elderly
- Authors:
- HARWOOD Dylan G., et al
- Journal article citation:
- International Journal of Geriatric Psychiatry, 19(12), December 2004, pp.1131-1139.
- Publisher:
- Wiley
This cross-sectional study examined the relationship between subjective memory complaints and the apolipoprotein epsilon 4 allele (4), a genetic risk factor for Alzheimer's disease (AD), among cognitively normal subjects identified from a community memory screening. The sample comprised 232 consecutive white non-Hispanic older adults who presented to a free community-based memory-screening program at a University affiliated memory disorders center. Participants were classified as cognitively normal based on scores on the age and educated adjusted Folstein Mini-Mental Status Exam (MMSAdj) and a brief Delayed Verbal Recall Test (DRT). Subjects were assessed for APOE genotype, subjective memory complaints (Memory Questionnaire, MQ), depressive symptoms (Hamilton Depression Rating Scale, HDRS), and history of four major medical conditions that have been associated with memory loss (stroke/transient ischemic attack [TIA], atherosclerotic heart disease, hypertension, and diabetes). A hierarchical regression analysis was performed to examine the association between APOE genotype and memory complaints after controlling for a host of potential confounding factors. The APOE 4 allele frequency for cognitively normal subjects was 0.13. Subjective memory complaints were predicted by depressive symptoms and a history of stroke/TIA. They were not associated with APOE genotype, MMSAdj score, DRT score, age, education, gender, and reported history of atherosclerotic heart disease, hypertension, or diabetes. The results did not suggest an association between subjective memory complaints and the APOE 4 allele in this sample of cognitively intact subjects. This indicates that memory complaints may confer risk for future dementia through pathways independent of APOE genotype. The results also show that older adults with memory complaints are at increased risk for underlying depression
Phantom boarder symptom in dementia
- Authors:
- HWANG Jen-Ping, YANG Chen-Hong, TSAI Shih-Jen
- Journal article citation:
- International Journal of Geriatric Psychiatry, 18(5), May 2003, pp.417-420.
- Publisher:
- Wiley
Phantom boarder symptom (PBS), which has been labelled a misidentification and is commonly observed in cases of Alzheimer's disease, is the perceptual dysfunction where it is imagined that there are people in the home. It may also be encountered in cases of vascular dementia and other variants of this cognitive dysfunction. This study was undertaken to investigate PBS frequency and characteristics for a sample of dementia inpatients, and to determine the strength of the association with other psychotic symptoms. The sample population consisted of 240 dementia patients admitted to our geropsychiatric ward. Patients with and without PBS were compared in terms of general characteristics and psychotic symptoms. Of the 240 dementia patients, PBS was identified in 56 (23.3%). There were no significant gender differences between the PBS and non-PBS groups. Means for age and onset-age were higher for the PBS group, and the prevalence of hallucinations and other misidentifications was greater compared to the non-PBS analog. Occurrence of PBS was not significantly associated with delusions or physical aggression. PBS is a common symptom in dementia of various etiologies. Our association findings suggest that it may be more productive to classify PBS as a type of misidentification, instead of as a delusion.
Emotional distress and morbidity in dementia carers: a matched comparison of husbands and wives
- Authors:
- COLLINS Chris, JONES Roberts
- Journal article citation:
- International Journal of Geriatric Psychiatry, 12(12), December 1997, pp.1168-1173.
- Publisher:
- Wiley
Aims to replicate previous findings that women experience more strain and distress than men when caring for dementing spouses, and explores what factors underlie this sex difference. Find that the wives' levels of strain and morale were found to be significantly worse than husbands'. There were qualitative differences between husbands and wives in terms of caregiving tasks undertaken. It is concluded that such attitudinal or social factors are the chief determinants of wives' higher levels of strain and distress.
Prevalence and correlates of aggressive behaviours occurring in patients with Alzheimer's Disease
- Authors:
- EASTLEY Rebecca, WILCOCK K. Gordon
- Journal article citation:
- International Journal of Geriatric Psychiatry, 12(4), April 1997, pp.484-487.
- Publisher:
- Wiley
The aim of the study was it determine the prevalence and clinical correlates of verbal and physical aggression occurring in Alzheimer's Disease (AD) sufferers. From the results it was concluded that aggressive behaviour is a common phenomenon in AD and approximately one in five suffers is assaultive. Assaultive behaviour is associated with male gender and dyspraxia.
A comprehensive support program: effect on depression in spouse-caregivers of AD patients
- Authors:
- MITTELMAN Mary S., et al
- Journal article citation:
- Gerontologist, 35(6), December 1995, pp.792-802.
- Publisher:
- Oxford University Press
Caregivers of Alzheimer's Disease patients often suffer from depression. Using a longitudinal treatment/control study, this article examines the effects of a comprehensive support programme on depression in spouse-caregivers. Results suggested that enhancing long-term social support can have a significant impact on depression in caregivers.
The impact of chronic illness on the health and well-being of family members
- Authors:
- LIEBERMAN Morton A., FISHER Lawrence
- Journal article citation:
- Gerontologist, 35(1), February 1995, pp.94-102.
- Publisher:
- Oxford University Press
Examines the impact of dementia on the physical and mental health of all family members caring for an ill parent/spouse. The sample included spouses of patients diagnosed with either Alzheimer's Disease or vascular dementia. Severity of illness was significantly associated with health and well-being for spouses, offspring, and in-laws, regardless of the amount of caregiving. Use of services displayed no direct association with spouse health and well-being, but service utilization interacted with illness severity. The relationship between severity of illness and spouse health was lower under conditions of high service utilization than under conditions of low service utilization.
Emotional reactions of lay persons to someone with Alzheimer's disease
- Authors:
- WERNER Perla, DAVIDSON Michael
- Journal article citation:
- International Journal of Geriatric Psychiatry, 19(4), April 2004, pp.391-397.
- Publisher:
- Wiley
Information about the nature of public reactions to people with Alzheimer's disease (AD) can help reduce stigmatization associated with the disease. The aim of this study was to examine emotional reactions to persons with AD, and its correlates. A total of 150 Jewish Israeli adults (mean age=59.9) were interviewed face-to-face regarding their emotional reactions to people with AD using a vignette methodology. Only a third of the participants gave the correct label. The person described in the vignette elicited more positive than negative emotions. Gender and perceived threat were the most important factors associated with emotional reactions. Findings suggest the need to expand the efforts to increase the recognition of AD by lay persons, and to address the negative emotions of several risk groups, such as male adults and those with greater concern about developing the disease.