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Complementary medicines in psychiatry: review of effectiveness and safety
- Authors:
- WERNEKE Ursula, TURNER Trevor, PRIEBE Stefan
- Journal article citation:
- British Journal of Psychiatry, 188(2), February 2006, pp.109-121.
- Publisher:
- Cambridge University Press
This article reviews the complementary medicines routinely encountered in psychiatric practice, their effectiveness, potential adverse effects and interactions. Electronic and manual literature search on the effectiveness and safety of psychotropic complementary medicines. Potentially useful substances include ginkgo and hydergine as cognitive enhancers, passion flower and valerian as sedatives, St John’s wort and s-adenosylmethionine as antidepressants, and selenium and folate to complement antidepressants. The evidence is less conclusive for the use of omega-3 fatty acids as augmentation treatment in schizophrenia, melatonin for tardive dyskinesia and 18-methoxycoronaridine, an ibogaine derivative, for the treatment of cocaine and heroin addiction. Systematic clinical trials are needed to test promising substances. Meanwhile, those wishing to take psychotropic complementary medicines require appropriate advice.
Choosing methods in mental health research: mental health research from theory to practice
- Editors:
- SLADE Mike, PRIEBE Stefan, (eds.)
- Publisher:
- Routledge
- Publication year:
- 2006
- Pagination:
- 298p., bibliog.
- Place of publication:
- London
This book is concerned with how to choose the most appropriate mental health research method, not only to address a specific question, but to maximize the potential impact on shaping mental health care. The editors focus attention on the types of audience that the researcher is seeking to influence, the types of evidence each audience accepts as valid, and the relative strengths and limitations of each type of methodology. A range of research methodologies are described and critically appraised, and the use of evidence by different groups is discussed. This produces some important findings about the interplay between research production and consumption, and highlights directions for future mental health research theory and practice. The findings presented here will be relevant to mental health service users and professionals who use research evidence to inform decision-making.
Assertive outreach teams in London: patient characteristics and outcomes: Pan-London Assertive Outreach Study, Part 3
- Authors:
- PRIEBE Stefan, et al
- Journal article citation:
- British Journal of Psychiatry, 183(8), August 2003, pp.148-154.
- Publisher:
- Cambridge University Press
Although the model of assertive outreach has been widely adopted, it is unclear who receives assertive outreach in practice and what outcomes can be expected under routine conditions. Patients (n=580) were sampled from 24 assertive outreach teams in London. Outcomes – days spent in hospital and compulsory hospitalisation – were assessed over a 9-month follow-up. The 6-month prevalence rate of substance misuse was 29%, and 35% of patients had been physically violent in the past 2 years. During follow-up, 39% were hospitalised and 25% compulsorily admitted. Outcome varied significantly between team types. These differences did not hold true when baseline differences in patient characteristics were controlled for. Routine assertive outreach serves a wide range of patients with significant rates of substance misuse and violent behaviour. Over a 9-month period an average of 25% of assertive outreach patients can be expected to be hospitalised compulsorily. Differences in outcome between team types can be explained by differences in patient characteristics.
Evidence in mental health care
- Editors:
- PRIEBE Stefan, SLADE Mike
- Publisher:
- Brunner-Routledge
- Publication year:
- 2002
- Pagination:
- 267p.,bibliog.
- Place of publication:
- Hove
This book evaluates a range of research methodologies and examines what types of 'evidence' have been appealed to. It comprises an historical and conceptual analysis of what was regarded as evidence and how this has impacted on mental health care. Presenting different methodological approaches it discusses their strengths and weaknesses in providing evidence, an how evidence is applied in different treatment and care modalities. Different angles on the the way forward for providing evidence to improve current treatments are scrutinised.