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A general practice-based prevalence study of epilepsy among adults with intellectual disabilities and of its association with psychiatric disorder, behaviour disturbance and carer stress
- Authors:
- MATTHEWS T., et al
- Journal article citation:
- Journal of Intellectual Disability Research, 52(2), February 2008, pp.163-173.
- Publisher:
- Wiley
The aims of this study were to determine the prevalence and features of epilepsy in a community-based population of adults with ID, and to explore whether the presence of epilepsy was associated with greater psychopathology or carer strain. Data were collected on the age, gender, place of residence, adaptive and challenging behaviour, social abilities and psychiatric status of 318 adults from 40 general practices in South and Mid Wales, together with the degree of malaise and strain of family carers. For participants with epilepsy, a nurse collected information on seizures, investigations, treatment and carer concerns by interview. Association between epilepsy and psychiatric morbidity, challenging behaviour and caregiver malaise or strain, was explored by comparing those with epilepsy with a comparison group matched on adaptive behaviour. Fifty-eight participants (18%) had epilepsy: 26% were seizure free, but 34% had extremely poorly controlled seizures. Earlier onset and seizure frequency were associated with adaptive behaviour. Carer concerns were related to seizure frequency and a history of injury. There were no significant differences in psychopathology, carer malaise or caregiver strain between the matched epilepsy and non-epilepsy groups. This study supports the high occurrence and chronicity of epilepsy among people with ID. While psychopathology and carer strain is common within this population, underlying disability-related factors appear to be more important than the presence of epilepsy per se.
Autism in adults: evidence update May 2014: a summary of selected new evidence relevant to NICE clinical guideline 142 ‘Autism: recognition, referral, diagnosis and management of adults on the autism spectrum’ (2012)
- Author:
- NATIONAL INSTITUTE FOR HEALTH AND CARE EXCELLENCE
- Publisher:
- National Institute for Health and Care Excellence
- Publication year:
- 2014
- Pagination:
- 19
- Place of publication:
- Manchester
This Evidence Update provides a summary of selected new evidence published since the literature search was last conducted for NICE clinical guideline 142 ‘Autism in adults’ (2012). A search was conducted for new evidence from 9 September 2011 to 27 November 2013 and a total of 4799 pieces of evidence were initially identified. The 29 most relevant references underwent a critical appraisal process and then were reviewed by an Evidence Update Advisory Group, which advised on the final list of 10 items selected for the Evidence Update. The update provides detailed commentaries on the new evidence focussing on general principles of care, assessment, interventions and monitoring, and organisation and delivery of care. The update shows that the new evidence does not have an impact on the existing guideline. (Edited publisher abstract)