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Ageing and dementia in a longitudinal study of a cohort with Down syndrome
- Authors:
- CARR Janet, COLLINS Suzanne
- Journal article citation:
- Journal of Applied Research in Intellectual Disabilities, 27(6), 2014, pp.555-563.
- Publisher:
- Wiley
Background: A population sample of people with Down syndrome has been studied from infancy and has now been followed up again at age 47 years. Methods: Intelligence and language skills were tested and daily living skills assessed. Memory/cognitive deterioration was examined using two test instruments. Results: Scores on verbal tests of intelligence changed little. Those on a non-verbal test, on self-help skills and on both memory tests showed some decline, even when the scores of those already suffering from dementia were discounted. Conclusions: At age 47, scores on most tests of even the majority of the cohort (i.e. those not definitely diagnosed with dementia) showed some decline. While this includes the scores of people who may subsequently develop dementia, it may also reflect the normal ageing process in this population. (Publisher abstract)
50 years with Down syndrome: a longitudinal study
- Authors:
- CARR Janet, COLLINS Suzanne
- Journal article citation:
- Journal of Applied Research in Intellectual Disabilities, 31(5), 2018, pp.743-750.
- Publisher:
- Wiley
Background: A population sample of people with Down syndrome, studied from infancy, has now been followed up at the age of 50 years. From the original sample of 54, there were 27 still in the study at the age of 50, all but four of the losses resulting from deaths. Methods: Intelligence and language skills were tested and daily living skills assessed. Memory/cognitive deterioration was examined using two test instruments. Other aspects of the people's lives were examined via carers' reports. Results: Scores on verbal tests showed little change. Those on a non‐verbal test, on self‐help skills and on both memory tests showed some decline, even when the scores of those already suffering from dementia were discounted. Conclusions: At the age of 50, those not already diagnosed with dementia showed some decline on most tests. While this may include scores of people who subsequently develop dementia, it may also reflect the normal ageing process in this population. (Edited publisher abstract)