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The first confirmed case of Down syndrome with dementia with Lewy bodies
- Authors:
- PRASHER V. P., AIRUEHIA E., CAREY M.
- Journal article citation:
- Journal of Applied Research in Intellectual Disabilities, 23(3), May 2010, pp.296-300.
- Publisher:
- Wiley
Dementia with Lewy bodies (DLB) is the second most common cause of dementia in the general population. Several researches have established an association between Down syndrome and Alzheimer's disease. Very few studies have, however, showed such an association between dementia with Lewy bodies and Down syndrome. The occurrence of dementia with Lewy bodies in persons with Down syndrome is widely unrecognised. This article reports the first case of a person with Down syndrome who fulfils the operational criteria for dementia with Lewy bodies and was also found to have Lewy bodies on neuropathological examination. The article emphasises the importance of making an early and accurate diagnosis as patients with dementia with Lewy bodies may respond differently than Alzheimer's dementia patients to certain behavioural and medical treatments.