Journal of Applied Research in Intellectual Disabilities, 27(6), 2014, pp.555-563.
Publisher:
Wiley
... ageing process in this population.
(Publisher abstract)
Background: A population sample of people with Down syndrome has been studied from infancy and has now been followed up again at age 47 years.
Methods: Intelligence and language skills were tested and daily living skills assessed. Memory/cognitive deterioration was examined using two test instruments.
Results: Scores on verbal tests of intelligence changed little. Those on a non-verbal test, on self-help skills and on both memory tests showed some decline, even when the scores of those already suffering from dementia were discounted.
Conclusions: At age 47, scores on most tests of even the majority of the cohort (i.e. those not definitely diagnosed with dementia) showed some decline. While this includes the scores of people who may subsequently develop dementia, it may also reflect the normal ageing process in this population.
(Publisher abstract)
Journal of Applied Research in Intellectual Disabilities, 31(5), 2018, pp.743-750.
Publisher:
Wiley
... showed some decline on most tests. While this may include scores of people who subsequently develop dementia, it may also reflect the normal ageing process in this population.
(Edited publisher abstract)
Background: A population sample of people with Down syndrome, studied from infancy, has now been followed up at the age of 50 years. From the original sample of 54, there were 27 still in the study at the age of 50, all but four of the losses resulting from deaths. Methods: Intelligence and language skills were tested and daily living skills assessed. Memory/cognitive deterioration was examined using two test instruments. Other aspects of the people's lives were examined via carers' reports. Results: Scores on verbal tests showed little change. Those on a non‐verbal test, on self‐help skills and on both memory tests showed some decline, even when the scores of those already suffering from dementia were discounted. Conclusions: At the age of 50, those not already diagnosed with dementia showed some decline on most tests. While this may include scores of people who subsequently develop dementia, it may also reflect the normal ageing process in this population.
(Edited publisher abstract)
Subject terms:
Downs syndrome, longitudinal studies, ageing, dementia, activities of daily living;
Journal of Applied Research in Intellectual Disabilities, 25(5), September 2012, pp.414-422.
Publisher:
Wiley
A population sample of 30 people with Down syndrome, repeatedly studied since infancy, has now been followed up at the age of 45 years. The paper provides an overview of their abilities over their life span to date, focusing particularly on the most recent 24 years. As at all previous occasions from age 30 onwards, intelligence, language, academic abilities and memory were tested, and self-help skills assessed. The most striking finding is the maintenance of test scores. Mean IQs, both non-verbal and verbal, changed little from age 21 to 45. Disregarding the scores of 2 women severely affected by dementia, the remainder of the cohort lost over the whole period an average of less than 1 point in non-verbal IQ and gained over 5 months in verbal age. Scores on memory tests by some of those not yet diagnosed with Alzheimer’s disease declined, in some cases significantly, suggesting that other members of the cohort too may be showing the early signs of the disease. The article concludes that most of the cohort show few indications of decline in ability. However, at the latest stage, a number now are or may be affected by Alzheimer’s disease, and this may require closer monitoring in the future.
A population sample of 30 people with Down syndrome, repeatedly studied since infancy, has now been followed up at the age of 45 years. The paper provides an overview of their abilities over their life span to date, focusing particularly on the most recent 24 years. As at all previous occasions from age 30 onwards, intelligence, language, academic abilities and memory were tested, and self-help skills assessed. The most striking finding is the maintenance of test scores. Mean IQs, both non-verbal and verbal, changed little from age 21 to 45. Disregarding the scores of 2 women severely affected by dementia, the remainder of the cohort lost over the whole period an average of less than 1 point in non-verbal IQ and gained over 5 months in verbal age. Scores on memory tests by some of those not yet diagnosed with Alzheimer’s disease declined, in some cases significantly, suggesting that other members of the cohort too may be showing the early signs of the disease. The article concludes that most of the cohort show few indications of decline in ability. However, at the latest stage, a number now are or may be affected by Alzheimer’s disease, and this may require closer monitoring in the future.
Subject terms:
memory, longitudinal studies, ageing, Alzheimers disease, communication skills, Downs syndrome;
Journal of Applied Research in Intellectual Disabilities, 16(1), March 2003, pp.29-40.
Publisher:
Wiley
A population sample with Down's syndrome which had been studied repeatedly since infancy, was then followed up again at age 35 years. Intelligence, language, reading and arithmetic were tested and daily living skills were assessed. Two memory tests, the Rivermead Behaviour Memory Test and Oliver and Crayton's Dementia Battery were given at age 30 years and again at age 35 years. Results from all the tests used showed little change from those found at 21 and/or 30 years.
A population sample with Down's syndrome which had been studied repeatedly since infancy, was then followed up again at age 35 years. Intelligence, language, reading and arithmetic were tested and daily living skills were assessed. Two memory tests, the Rivermead Behaviour Memory Test and Oliver and Crayton's Dementia Battery were given at age 30 years and again at age 35 years. Results from all the tests used showed little change from those found at 21 and/or 30 years.
Subject terms:
learning disabilities, personality development, problem solving, severe mental health problems, statistical methods, ageing, diagnostic tests, Downs syndrome;